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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGKD All Species: 19.7
Human Site: S532 Identified Species: 43.33
UniProt: Q16760 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16760 NP_003639.2 1214 134525 S532 T T E S S E E S E V M A K K C
Chimpanzee Pan troglodytes XP_001151474 1220 134870 V543 N A V V A D A V A S K C S V L
Rhesus Macaque Macaca mulatta XP_001114920 1167 129871 S488 T T E S S E E S E V M A K K C
Dog Lupus familis XP_543293 1324 146248 S642 T T E S S E E S E V M A K K C
Cat Felis silvestris
Mouse Mus musculus NP_808314 1220 135190 S532 T T E S S Q E S E V M A K K C
Rat Rattus norvegicus XP_347259 1196 133109 S512 T T E S S Q E S E V M A K K C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507672 1254 138458 A573 E N T D E A D A M S V K C S V
Chicken Gallus gallus XP_001232791 1333 149344 A650 E N A D E A D A M A I K C S E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693512 1148 127826 K477 L D K L S L H K Q C Q L G V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A8JQ65 1895 211641 R564 A V K C D I L R Q K L N M L L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202627 1158 127377 T470 T S G G G M G T P T I L P R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.2 93.4 85.1 N.A. 93.7 90.2 N.A. 66.9 63.9 N.A. 60.9 N.A. 34.8 N.A. N.A. 53.3
Protein Similarity: 100 76.3 94.1 87.8 N.A. 96.4 93.3 N.A. 77.4 73.8 N.A. 71.6 N.A. 46.5 N.A. N.A. 65.8
P-Site Identity: 100 0 100 100 N.A. 93.3 93.3 N.A. 0 0 N.A. 6.6 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 20 20 N.A. 20 N.A. 20 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 10 19 10 19 10 10 0 46 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 10 0 10 19 0 46 % C
% Asp: 0 10 0 19 10 10 19 0 0 0 0 0 0 0 0 % D
% Glu: 19 0 46 0 19 28 46 0 46 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 10 10 0 10 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 19 0 0 0 0 % I
% Lys: 0 0 19 0 0 0 0 10 0 10 10 19 46 46 0 % K
% Leu: 10 0 0 10 0 10 10 0 0 0 10 19 0 10 28 % L
% Met: 0 0 0 0 0 10 0 0 19 0 46 0 10 0 0 % M
% Asn: 10 19 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 19 0 0 19 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % R
% Ser: 0 10 0 46 55 0 0 46 0 19 0 0 10 19 10 % S
% Thr: 55 46 10 0 0 0 0 10 0 10 0 0 0 0 0 % T
% Val: 0 10 10 10 0 0 0 10 0 46 10 0 0 19 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _